25^th American Dental Research & Future Dentistry

Oral mucositis is one of the serious side effects of chemotherapy and radiotherapy. Complications secondary to oral mucositis include ulcers, pain, dysphagia, dysgeusia, infection, eating and breathing problems, as well as mucositis on the gum and dental condition of patients. Mucositis can affect the patient’s self-confidence and reduces the quality of life of by reducing the ability to communicate. The purpose of this study was to evaluate the diet of a person under cancer treatment on the severity of chemotherapy and radiation therapy induced mucositis. Twenty-one cancer patients who referred to Imam Khomeini Hospital in the middle of the cancer treatment phase and completed the first stage of chemotherapy and were waiting for their next stage of treatment, were randomly selected. At this stage, the patients were examined by

a dental and oral dentist and the severity of mucositis was determined by a dentist according to the World Health Organization (WHO) criteria. Completion of diary for 3 days, Allergen nutrient inventory and nutritional recommendations were completed at this stage. After completion of the forms, 4 questionnaires were completed for each patient and the diet of patients was analyzed in N4 software and the amount of macro and micronutrients were

determined. Afterwards, the relation of dietary intake with the severity of oral mucositis (Grade 1 to 4) was investigated. For analyze of regression model SPSS software was used. (P <0.05) In this study, among all the studied micro and macronutrients: the micronutrients of the amino acids aspartic acid, glycine, proline, alanine, arginine, glutamic acid and vitamin b12, and macronutrients including rose water, coffee and veal, there was a significant difference between group 1 (grade 1 mucositis) and group 2 (grade 2 mucositis). It can be concluded from this cross-sectional study that diet is effective on the severity of mucositis caused by cancer treatments.